Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | RORC | P51449 | 7/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.35 |
| ▸ | GLRB | P48167 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30185534 | 0.72 | RORC (0.57) | KIF11CYP2C9RORC | |
| SCHEMBL30185517 | 0.71 | KIF11 (0.62) | KIF11CYP2C9RORC | |
| SCHEMBL30185518 | 0.71 | KIF11 (0.47) | KIF11CYP2C9RORC | |
| SCHEMBL27688435 | 0.66 | MAOB (0.44) | KIF11CYP2C9SIRT2SIRT1MAOB | |
| SCHEMBL28296039 | 0.65 | ALDH1A1 (0.45) | OPRM1OPRD1OPRK1SIRT2KDM4E | |
| SCHEMBL18954610 | 0.64 | CHRM5 (0.69) | MAOBALDH1A1 | |
| SCHEMBL28576798 | 0.63 | RORC (0.72) | RORC | |
| SCHEMBL27933685 | 0.61 | MAOB (0.53) | KIF11CYP2C9MAOBCYP3A4 | |
| SCHEMBL26132798 | 0.61 | ALDH1A1 (0.46) | OPRM1OPRD1OPRK1SIRT2KDM4E | |
| SCHEMBL27808823 | 0.61 | KDM4E (0.60) | SIRT2SIRT1KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759541-B | Indole-like derivatives and uses thereof | 复旦大学 | 2023-03-17 | — | — | CN | disclosed |