Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | MST1R | Q04912 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15365507 | 0.80 | TDO2 (0.46) | TDO2ADORA3KCNH2KDM4EALDH1A1 | |
| SCHEMBL1284851 | 0.80 | ALDH1A1 (0.49) | TDO2KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL1060974 | 0.79 | ADORA3 (0.56) | TDO2ADORA3KCNH2KDM4EALDH1A1 | |
| SCHEMBL24181830 | 0.77 | LTK (0.40) | TDO2KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL13029774 | 0.77 | ALDH1A1 (0.44) | TDO2ADORA3KCNH2KDM4EALDH1A1 | |
| SCHEMBL28746780 | 0.77 | TSHR (0.48) | TDO2ADORA3KCNH2KDM4EALDH1A1 | |
| SCHEMBL4196237 | 0.76 | ALDH1A1 (0.50) | KDM4EALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL31607601 | 0.76 | ALDH1A1 (0.50) | KDM4EALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL5776802 | 0.73 | ADORA1 (0.55) | ADORA3KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL2009428 | 0.73 | KCNH2 (0.50) | TDO2ADORA3KCNH2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611868-B | Furanamide derivative and preparation method and application thereof | 山东大学 | 2024-07-23 | — | — | CN | claimed |
| CN-115611868-A | Furanamide derivative and preparation method and application thereof | 山东大学 | 2023-01-17 | — | — | CN | claimed |
| CN-115611868-B | Furanamide derivative and preparation method and application thereof | 山东大学 | 2024-07-23 | — | — | CN | disclosed |
| CN-115611868-A | Furanamide derivative and preparation method and application thereof | 山东大学 | 2023-01-17 | — | — | CN | disclosed |