Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 2/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29120582 | 1.00 | CPN1 (0.36) | CPN1CPB2SLC6A1GABRA5GABRB2 | |
| SCHEMBL4272078 | 0.91 | CPN1 (0.47) | CPN1CPB2SLC6A1SLC6A11SLC6A13 | |
| SCHEMBL1129311 | 0.90 | CPN1 (0.41) | CPN1CPB2GABRA5GABRB2GABRA1 | |
| SCHEMBL5135071 | 0.89 | KMT2A (0.34) | CPN1CPB2SLC6A4SLC6A3 | |
| SCHEMBL27192552 | 0.81 | CHRM2 (0.33) | — | |
| SCHEMBL25337412 | 0.81 | BRPF1 (0.32) | CPN1CPB2SLC6A1GABRA5GABRB2 | |
| SCHEMBL28103000 | 0.81 | CPN1 (0.31) | CPN1CPB2SLC6A1GABRA5GABRB2 | |
| SCHEMBL7383261 | 0.79 | SLC6A1 (0.33) | CPN1CPB2SLC6A1GABRA5GABRB2 | |
| SCHEMBL7390438 | 0.79 | SLC6A1 (0.33) | CPN1CPB2SLC6A1GABRA5GABRB2 | |
| SCHEMBL4312543 | 0.79 | SLC6A1 (0.33) | CPN1CPB2SLC6A1GABRA5GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617256-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20170088549-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2017-03-30 | — | — | US | disclosed |
| EP-2170814-B1 | ANTIBACTERIAL AGENTS | ACHAOGEN INC (US) | 2016-08-17 | — | — | EP | disclosed |
| EP-2662353-A2 | Antibacterial agents | Achaogen, Inc. (US) | 2013-11-13 | — | — | EP | disclosed |
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088549-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | CPN1 2942/4885CPB2 1737/4885SLC6A1 1296/4885 |
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | CPN1 2942/4885CPB2 1737/4885SLC6A1 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.