Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 9/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 9/20 | 0.45 |
| ▸ | CPN1 | P15169 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31688938 | 0.87 | CPN1 (0.42) | AKR1C3AKR1C2CPN1CPB2MEN1 | |
| SCHEMBL16963923 | 0.81 | CES2 (0.46) | AKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL25002472 | 0.78 | PKM (0.43) | AKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL27643664 | 0.78 | CPN1 (0.38) | CPN1CPB2MEN1CYP1A2CYP3A4 | |
| SCHEMBL1489632 | 0.77 | KCNQ2 (0.50) | MEN1CYP3A4KMT2A | |
| SCHEMBL30192806 | 0.77 | PSEN1 (0.48) | AKR1C3AKR1C2MEN1CYP1A2CYP3A4 | |
| SCHEMBL24875683 | 0.77 | PSEN1 (0.48) | AKR1C3AKR1C2MEN1CYP1A2CYP3A4 | |
| SCHEMBL30821928 | 0.77 | KCNQ2 (0.50) | MEN1CYP3A4KMT2A | |
| SCHEMBL4658268 | 0.77 | LMNA (0.48) | AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL29009806 | 0.76 | AKR1C3 (0.40) | AKR1C3AKR1C2PPARDPPARAAKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121055-A1 | STAT DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |