Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24875667 | 1.00 | NOTUM (0.41) | NOTUMSOS1AAK1LMNAAKR1C3 | |
| SCHEMBL16207402 | 0.83 | AAK1 (0.37) | AAK1LMNAMT-CO2MEN1NPC1 | |
| SCHEMBL16216397 | 0.83 | AAK1 (0.37) | AAK1LMNAMT-CO2MEN1NPC1 | |
| SCHEMBL24875505 | 0.77 | PSEN1 (0.41) | NOTUMAKR1C3AKR1C2SMN1; SMN2S1PR1 | |
| SCHEMBL19182794 | 0.77 | DPP4 (0.41) | NOTUMAKR1C3AKR1C2S1PR1MT-CO2 | |
| SCHEMBL16216371 | 0.70 | MT-CO2 (0.40) | LMNAAKR1C3AKR1C2MT-CO2MEN1 | |
| SCHEMBL16207548 | 0.70 | MT-CO2 (0.40) | LMNAAKR1C3AKR1C2MT-CO2MEN1 | |
| SCHEMBL2130305 | 0.70 | APLNR (0.50) | AAK1LMNASMN1; SMN2MT-CO2NPC1 | |
| SCHEMBL21096066 | 0.70 | ALDH1A1 (0.41) | LMNASMN1; SMN2MT-CO2MEN1NPC1 | |
| SCHEMBL8321208 | 0.70 | MT-CO2 (0.47) | LMNAAKR1C3AKR1C2MT-CO2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4366829-A1 | PHENYL ACETAMIDE BASED IL-17A MODULATORS AND USES THEREOF | Dice Alpha, Inc. (US) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023283453-A1 | PHENYL ACETAMIDE BASED IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2023-01-12 | — | — | WO | disclosed |