Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 3/20 | 0.33 |
| ▸ | APLNR | P35414 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16207402 | 1.00 | AAK1 (0.37) | AAK1MT-CO2PTGS1PTGS2MEN1 | |
| SCHEMBL30193017 | 0.83 | NOTUM (0.41) | AAK1MT-CO2PTGS1PTGS2MEN1 | |
| SCHEMBL24875667 | 0.83 | NOTUM (0.41) | AAK1MT-CO2PTGS1PTGS2MEN1 | |
| SCHEMBL16216371 | 0.83 | MT-CO2 (0.40) | MT-CO2PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL16207548 | 0.83 | MT-CO2 (0.40) | MT-CO2PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL28754394 | 0.81 | PTGS1 (0.42) | PTGS1PTGS2MEN1KMT2ALMNA | |
| SCHEMBL16216461 | 0.81 | MAOB (0.37) | MT-CO2PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL16207546 | 0.81 | MAOB (0.37) | MT-CO2PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL16216459 | 0.80 | MT-CO2 (0.35) | MT-CO2PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL16207626 | 0.80 | MT-CO2 (0.35) | MT-CO2PTGS1PTGS2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221786-B2 | 2-fluorophenyl propionic acid derivatives | LTT BIO-PHARMA CO., LTD. (JP) | 2015-12-29 | — | — | US | disclosed |
| US-9221786-B2 | 2-fluorophenyl propionic acid derivatives | LTT BIO-PHARMA CO., LTD. (JP) | 2015-12-29 | — | — | US | disclosed |
| US-20140330026-A1 | 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES | LTT BIO-PHARMA CO., LTD. (JP) | 2014-11-06 | — | — | US | disclosed |
| US-20140330026-A1 | 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES | LTT BIO-PHARMA CO., LTD. (JP) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330026-A1 | 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES | FPR1, OPRK1, FPR2 | AAK1 2197/4885MT-CO2 1253/4885PTGS1 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.