Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5273904 | 1.00 | PSIP1 (0.40) | PSIP1CCR2L3MBTL1LOXL2CA1 | |
| Hydrochloric Acid SCHEMBL5278745 | 0.98 | CA1 (0.40) | PSIP1CCR2L3MBTL1LOXL2CA1 | |
| SCHEMBL17315470 | 0.87 | F2 (0.46) | L3MBTL1CA1CA2CA12CA4 | |
| SCHEMBL29744376 | 0.83 | CA2 (0.48) | PSIP1LOXL2CA1CA2CA12 | |
| SCHEMBL13211316 | 0.83 | GPR119 (0.42) | CCR2L3MBTL1CA2GPR119KCNH2 | |
| SCHEMBL19941004 | 0.83 | CA2 (0.48) | PSIP1LOXL2CA1CA2CA12 | |
| Hydrochloric Acid SCHEMBL19859178 | 0.81 | CA2 (0.50) | PSIP1LOXL2CA1CA2CA12 | |
| SCHEMBL30457289 | 0.81 | CCR2 (0.40) | CCR2L3MBTL1GPR119KCNH2CHRM4 | |
| SCHEMBL1940032 | 0.81 | CYP4F2 (0.44) | CCR2CA1CA2CA12CA4 | |
| SCHEMBL1940002 | 0.81 | CCR2 (0.40) | CCR2L3MBTL1GPR119KCNH2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115776891-A | STAT degradants and uses thereof | 凯麦拉医疗公司 | 2023-03-10 | — | — | CN | disclosed |
| EP-4121055-A1 | STAT DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |