Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.53 |
| ▸ | MMP3 | P08254 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31655757 | 0.90 | FPR2 (0.51) | — | |
| SCHEMBL31293776 | 0.89 | OPRD1 (0.55) | MMP1MMP3MMP9MAPTTDP1 | |
| SCHEMBL29484050 | 0.85 | MMP1 (0.55) | MMP1MMP3MMP9MAPTTDP1 | |
| SCHEMBL30179666 | 0.85 | OPRD1 (0.45) | MMP1MMP3MMP9ABCB1OPRK1 | |
| SCHEMBL29468054 | 0.85 | PLG (0.47) | MMP1MMP3MMP9ABCB1CTSK | |
| SCHEMBL30565190 | 0.85 | MMP1 (0.45) | MMP1MMP3MMP9ABCB1ACACB | |
| SCHEMBL1437012 | 0.85 | MMP1 (0.57) | MMP1MMP3MMP9MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL29468048 | 0.84 | PLG (0.46) | MMP1MMP3MMP9ABCB1CTSK | |
| SCHEMBL7096621 | 0.84 | MMP1 (0.54) | MMP1MMP3MMP9MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL5966853 | 0.83 | MMP1 (0.56) | MMP1MMP3MMP9MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3510399-B1 | PSMA-TARGETED NIR DYES AND THEIR USES | ON TARGET LABORATORIES LLC (US) | 2023-03-01 | — | — | EP | disclosed |