SCHEMBL30197653

SCHEMBL30197653

CCCc1c(C)c(C)nc2ccccc12

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.70
KDM4E B2RXH2 4/20 0.70
HPGD P15428 2/20 0.70
GAA P10253 1/20 0.70
HTT P42858 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
KMT2A Q03164 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
GPR3 P46089 1/20 0.50
PDE10A Q9Y233 2/20 0.49
TLR8 Q9NR97 4/20 0.47
HSD17B10 Q99714 3/20 0.46
CYP1A2 P05177 2/20 0.46
NUDT1 P36639 1/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
ELANE P08246 1/20 0.45
POLB P06746 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
MAPK1 P28482 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28985726 1.00 ALDH1A1 (0.70) ALDH1A1KDM4EHPGDGAAHTT
SCHEMBL10496106 0.85 GPR3 (0.53) ALDH1A1KDM4EHPGDGAAHTT
SCHEMBL3343659 0.83 KDM4E (1.00) ALDH1A1KDM4EHPGDGAAHTT
SCHEMBL3970688 0.81 PDE10A (0.56) ALDH1A1KDM4EHPGDGAAHTT
SCHEMBL3970686 0.80 PDE10A (0.54) ALDH1A1KDM4EHPGDGAAHTT
SCHEMBL32659735 0.79 ALDH1A1 (0.61) ALDH1A1KDM4EHPGDGAAHTT
SCHEMBL25820158 0.77 GPR3 (0.48) ALDH1A1KDM4EHPGDGAAHTT
SCHEMBL3731476 0.76 KDM4E (0.78) ALDH1A1KDM4EHPGDGAAHTT
Acridine SCHEMBL21810741 0.75 KDM4E (0.82) ALDH1A1KDM4EHPGDGAAHTT
SCHEMBL231530 0.74 GPR3 (0.64) ALDH1A1KDM4EHPGDHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115836041-A Process for producing optically active compound 住友化学株式会社 2023-03-21 CN disclosed