SCHEMBL3019783

SCHEMBL3019783

C=C(C)C1(C=O)CC=C(C)CC1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11663739 0.73 LMNA (0.31) LMNA
SCHEMBL3012794 0.72
SCHEMBL29209964 0.71 LMNA (0.36) LMNA
SCHEMBL524697 0.71 LMNA (0.36) LMNA
SCHEMBL29209906 0.71 LMNA (0.36) LMNA
SCHEMBL3025862 0.69
SCHEMBL25905861 0.68 GLI1 (0.35)
SCHEMBL11360762 0.68 GLI1 (0.35)
SCHEMBL3019242 0.68
SCHEMBL3023176 0.67 LMNA (0.31) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3112338-A2 CYCLOHEXENE DERIVATIVES AND THEIR USE AS ODORANTS Givaudan SA (CH) 2017-01-04 EP claimed
US-8691746-B2 Cyclohexene derivatives and their use as odorants GIVAUDAN SA (CH) 2014-04-08 US claimed
US-8304380-B2 Cyclohexene derivatives and their use as odorants GIVAUDAN SA (CH) 2012-11-06 US claimed
EP-3112338-B1 CYCLOHEXENE DERIVATIVES AND THEIR USE AS ODORANTS GIVAUDAN SA (CH) 2021-09-29 EP disclosed
EP-3112338-A2 CYCLOHEXENE DERIVATIVES AND THEIR USE AS ODORANTS Givaudan SA (CH) 2017-01-04 EP disclosed
US-8691746-B2 Cyclohexene derivatives and their use as odorants GIVAUDAN SA (CH) 2014-04-08 US disclosed
US-20130035278-A1 Cyclohexene Derivatives and Their Use as Odorants GIVAUDAN SA (CH) 2013-02-07 US disclosed
US-8304380-B2 Cyclohexene derivatives and their use as odorants GIVAUDAN SA (CH) 2012-11-06 US disclosed
US-20100204084-A1 Cyclohexene Derivatives and Their Use as Odorants GIVAUDAN SA (CH) 2010-08-12 US disclosed
EP-2188242-A2 CYCLOHEXENE DERIVATIVES AND THEIR USE AS ODORANTS Givaudan SA (CH) 2010-05-26 EP disclosed
WO-2009021342-A2 CYCLOHEXENE DERIVATIVES AND THEIR USE AS ODORANTS GIVAUDAN SA (CH) 2009-02-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130035278-A1 Cyclohexene Derivatives and Their Use as Odorants ESD, DHPS, BBOX1 LMNA 951/4885
US-20100204084-A1 Cyclohexene Derivatives and Their Use as Odorants ESD, DHPS, BBOX1 LMNA 951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.