Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25090325 | 1.00 | GRM5 (0.44) | GRM5MEN1KMT2AALDH1A1TACR1 | |
| SCHEMBL29328325 | 0.89 | TACR1 (0.42) | GRM5MEN1KMT2ATACR1POLB | |
| SCHEMBL25090456 | 0.82 | L3MBTL1 (0.51) | MEN1KMT2AALDH1A1TACR1SMN1; SMN2 | |
| SCHEMBL16490799 | 0.80 | MEN1 (0.47) | GRM5MEN1KMT2AALDH1A1POLB | |
| SCHEMBL30201225 | 0.80 | ALDH1A1 (0.45) | GRM5MEN1KMT2AALDH1A1TACR1 | |
| SCHEMBL25090505 | 0.80 | ALDH1A1 (0.45) | GRM5MEN1KMT2AALDH1A1TACR1 | |
| SCHEMBL4479936 | 0.80 | LMNA (0.42) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL2350223 | 0.77 | ADORA1 (0.42) | GRM5ALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL5246761 | 0.76 | CNR1 (0.39) | GRM5MEN1KMT2ANPC1 | |
| SCHEMBL5246764 | 0.76 | CNR1 (0.39) | GRM5MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028056-A1 | 3-AMINO PIPERIDYL SODIUM CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |