Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246761 | 0.89 | CNR1 (0.39) | MEN1KMT2AGRM5GAAGRM1 | |
| SCHEMBL5246757 | 0.89 | CNR1 (0.39) | MEN1KMT2AGRM5GAAGRM1 | |
| SCHEMBL5246764 | 0.89 | CNR1 (0.39) | MEN1KMT2AGRM5GAAGRM1 | |
| SCHEMBL4479936 | 0.88 | LMNA (0.42) | MEN1KMT2AALDH1A1GPR119L3MBTL1 | |
| SCHEMBL25090325 | 0.80 | GRM5 (0.44) | MEN1KMT2AALDH1A1POLBHTT | |
| SCHEMBL30201137 | 0.80 | GRM5 (0.44) | MEN1KMT2AALDH1A1POLBHTT | |
| SCHEMBL5230371 | 0.80 | GPR119 (0.38) | ALDH1A1GPR119L3MBTL1TDP1CYP3A4 | |
| SCHEMBL22309108 | 0.80 | MEN1 (0.68) | MEN1KMT2AALDH1A1GPR119L3MBTL1 | |
| SCHEMBL2350223 | 0.80 | ADORA1 (0.42) | ALDH1A1GRM5GLA | |
| SCHEMBL6414267 | 0.79 | CYP11B2 (0.36) | KMT2AALDH1A1GPR119L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617244-B2 | Antibacterial quinoline derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2017-04-11 | — | — | US | disclosed |
| US-9617244-B2 | Antibacterial quinoline derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2017-04-11 | — | — | US | disclosed |
| US-20150051244-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN-CILAG (FR) | 2015-02-19 | — | — | US | disclosed |
| US-20150051244-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN-CILAG (FR) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051244-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | NQO2, NDUFB5, NDUFB7 | MEN1 3002/4885KMT2A 4034/4885ALDH1A1 2506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.