Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.59 |
| ▸ | PLAU | P00749 | 1/20 | 0.59 |
| ▸ | NOS3 | P29474 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145593 | 0.75 | — | — | |
| SCHEMBL4316417 | 0.74 | ADRA2A (0.63) | ADRA2AADRA2BADRA2CPLAUNOS3 | |
| SCHEMBL2226462 | 0.74 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CPLAUNOS3 | |
| SCHEMBL2729935 | 0.71 | ADRA2A (0.59) | ADRA2AADRA2BADRA2CPLAUNOS3 | |
| SCHEMBL4021935 | 0.71 | ADRA2A (0.70) | ADRA2AADRA2BADRA2CPLAUNOS3 | |
| SCHEMBL1703431 | 0.71 | ADRA2A (0.70) | ADRA2AADRA2BADRA2CPLAUNOS3 | |
| SCHEMBL1852788 | 0.70 | — | — | |
| SCHEMBL4406611 | 0.69 | ADRA2A (0.57) | ADRA2AADRA2BADRA2CPLAUNOS3 | |
| SCHEMBL275526 | 0.69 | MAOA (0.77) | ADRA2AADRA2BADRA2CPLAUMAOA | |
| SCHEMBL718626 | 0.69 | ADRA2A (0.56) | ADRA2AADRA2BADRA2CPLAUNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230053638-A1 | PHOTOSWITCHABLE GUANIDINIUM COMPOUNDS FOR REMOVAL OF OXYANIONS FROM LIQUID SOLUTIONS | U. S. DEPARTMENT OF ENERGY | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230053638-A1 | PHOTOSWITCHABLE GUANIDINIUM COMPOUNDS FOR REMOVAL OF OXYANIONS FROM LIQUID SOLUTIONS | CHRM1, CHRM2, CHRM4 | ADRA2A 897/4885ADRA2B 798/4885ADRA2C 611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.