Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | PHGDH | O43175 | 2/20 | 0.53 |
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31530751 | 0.89 | KDM4E (0.69) | HTTKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL30714864 | 0.78 | MAPT (0.61) | HTTKDM4EDUSP3PTPN5PTPN11 | |
| SCHEMBL8433110 | 0.78 | MAPT (0.75) | HTTKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL25243618 | 0.78 | MAPT (0.75) | HTTKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL15457450 | 0.77 | MEN1 (0.77) | HTTKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL1520466 | 0.77 | KDM4E (0.64) | HTTKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL7748744 | 0.77 | KDM4E (0.64) | HTTKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL28508004 | 0.76 | MEN1 (0.73) | HTTKDM4EDUSP3PTPN5PTPN11 | |
| SCHEMBL6742179 | 0.76 | GPR35 (0.51) | HTTKDM4EMAPTKMT2AMEN1 | |
| Water SCHEMBL6576230 | 0.76 | KDM4E (0.62) | HTTKDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11565995-B2 | Methods of forming imines, imine-related and imine-derived compounds using green solvents | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11565995-B2 | Methods of forming imines, imine-related and imine-derived compounds using green solvents | IK, LDHB, IDH3B | HTT 3590/4885KDM4E 2545/4885DUSP3 2038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.