Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 3/20 | 0.49 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10809119 | 0.83 | HSD17B10 (0.39) | CDC7PDE3BPDE3APDE4APDE4B | |
| SCHEMBL10989494 | 0.81 | HSP90AB1 (0.42) | CDC7PDE3BPDE3APDE4APDE4B | |
| SCHEMBL9631567 | 0.77 | TSHR (0.50) | MAPTMEN1LMNAKMT2AGABRA1 | |
| SCHEMBL10682419 | 0.77 | LMNA (0.39) | CDC7PDE3BPDE3APDE4APDE4B | |
| SCHEMBL10676916 | 0.75 | ALDH1A1 (0.46) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL30497772 | 0.75 | BRD4 (0.47) | CDC7PARP1BRD4MAPTLMNA | |
| SCHEMBL10680196 | 0.74 | PDE3B (0.58) | CDC7PDE3BPDE3APDE4APDE4B | |
| SCHEMBL10672837 | 0.73 | CCND3 (0.38) | PDE3BPDE3AMAPTKDM4ETSHR | |
| SCHEMBL10683064 | 0.72 | NPC1 (0.50) | PDE4APDE4DMAPTMEN1LMNA | |
| SCHEMBL10679651 | 0.72 | ADORA2A (0.46) | MAPTMEN1LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023022497-A1 | SOS1 INHIBITOR AND USE THEREOF | 주식회사 카나프테라퓨틱스 | 2023-02-23 | — | — | WO | disclosed |