Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND3 | P30281 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677472 | 0.79 | NPC1 (0.38) | CCND3CDK6TSHRCYP1A2KDM4E | |
| SCHEMBL10675813 | 0.78 | NAPRT (0.43) | CCND3CDK6TSHRCYP1A2KDM4E | |
| SCHEMBL10678506 | 0.78 | CYP1A2 (0.39) | CCND3CDK6TSHRCYP1A2KDM4E | |
| SCHEMBL10684504 | 0.77 | CDC7 (0.40) | CCND3CDK6TSHRCYP1A2KDM4E | |
| SCHEMBL10676916 | 0.76 | ALDH1A1 (0.46) | MAPTL3MBTL1PDE3BPDE3ANPC1 | |
| SCHEMBL10679720 | 0.75 | PDE3B (0.45) | CYP1A2KDM4ESMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL10682419 | 0.75 | LMNA (0.39) | TSHRCYP1A2MAPTCYP2D6PDE3B | |
| SCHEMBL7431281 | 0.75 | PDE3B (0.58) | CCND3CDK6TSHRPDE3BPDE3A | |
| SCHEMBL10680196 | 0.75 | PDE3B (0.58) | CYP1A2KDM4ECYP2D6PDE3BPDE3A | |
| SCHEMBL10676194 | 0.74 | ALDH1A1 (0.52) | TSHRKDM4EMAPTL3MBTL1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |