Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 5/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10676916 | 0.86 | ALDH1A1 (0.46) | LMNAPDE3BPDE3APDE4DGAA | |
| SCHEMBL10683064 | 0.82 | NPC1 (0.50) | LMNACYP1A2PDE4DCYP2C19CYP2C9 | |
| SCHEMBL10680196 | 0.82 | PDE3B (0.58) | LMNACYP1A2CYP3A4PDE3BPDE3A | |
| SCHEMBL10680841 | 0.80 | MAPK1 (0.45) | LMNATSHRHTTGAAMAPT | |
| SCHEMBL10675823 | 0.79 | CDC7 (0.38) | LMNACYP1A2CYP3A4MAOAPDE3B | |
| SCHEMBL10678457 | 0.78 | LMNA (0.40) | LMNACYP1A2CYP3A4MAOAPDE3B | |
| SCHEMBL10681929 | 0.77 | CDC7 (0.42) | LMNACYP1A2CYP3A4MAOAPDE3B | |
| SCHEMBL10684520 | 0.77 | UCHL1 (0.46) | LMNACYP1A2CYP3A4MAOAPDE3B | |
| SCHEMBL30202740 | 0.77 | CDC7 (0.49) | LMNACYP3A4PDE3BPDE3APDE4D | |
| SCHEMBL10675744 | 0.77 | DRD2 (0.38) | CYP1A2CYP3A4PDE3BPDE3APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |