SCHEMBL30205203

SCHEMBL30205203

C=Cc1ccc(C[Si])cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 2/20 0.39
HDAC8 Q9BY41 1/20 0.39
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
POLB P06746 1/20 0.34
TP53 P04637 3/20 0.33
MAPT P10636 3/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 2/20 0.32
PSMD14 O00487 1/20 0.32
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50300 0.80 ALDH1A1 (0.65) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL1647493 0.80 ALDH1A1 (0.65) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL50012 0.80 ALDH1A1 (0.65) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL473081 0.78 ALDH1A1 (1.00) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL7639 0.78 ALDH1A1 (1.00) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL248030 0.78 ALDH1A1 (0.61) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL171622 0.76 ALDH1A1 (0.58) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL3436515 0.76 ALDH1A1 (0.58) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL18727870 0.76 ALDH1A1 (0.58) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL1900855 0.76 ALDH1A1 (0.58) ALDH1A1TSHRTDP1HDAC8CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115819672-A Profile control agent, preparation method and application 中国石油化工股份有限公司 2023-03-21 CN claimed
CN-115819672-A Profile control agent, preparation method and application 中国石油化工股份有限公司 2023-03-21 CN disclosed
CN-115819672-A Profile control agent, preparation method and application 中国石油化工股份有限公司 2023-03-21 CN disclosed