SCHEMBL248030

SCHEMBL248030

[CH2]Cc1ccc(C=C)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 2/20 0.39
HDAC8 Q9BY41 1/20 0.39
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
POLB P06746 1/20 0.34
TP53 P04637 3/20 0.33
MAPT P10636 3/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 2/20 0.32
PSMD14 O00487 1/20 0.32
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6380427 0.81 ALDH1A1 (0.58) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL50300 0.80 ALDH1A1 (0.65) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL1647493 0.80 ALDH1A1 (0.65) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL50012 0.80 ALDH1A1 (0.65) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL5145772 0.79 ALDH1A1 (0.55) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL473081 0.78 ALDH1A1 (1.00) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL7639 0.78 ALDH1A1 (1.00) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL1803971 0.78 ESR1 (0.32) ALDH1A1TSHRTDP1
SCHEMBL30205203 0.78 ALDH1A1 (0.61) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL1900855 0.76 ALDH1A1 (0.58) ALDH1A1TSHRTDP1HDAC8CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 452 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5098981-A POLYORGANOSILOXANE CHISSO CORPORATION (JP) 1992-03-24 US claimed
EP-0349920-A2 Polyorganosiloxane Chisso Corporation (JP) 1990-01-10 EP claimed
CN-114981329-B Radiation polymerizable composition, cured layer thereof, optical fiber containing cured layer and production method thereof 日本精涂层株式会社 2024-06-21 CN disclosed
CN-118234822-A Adhesive composition, adhesive sheet, electromagnetic wave shielding film, laminate, and printed wiring board 东洋纺艾睦希株式会社 2024-06-21 CN disclosed
WO-2024113195-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESSTHEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE DOW TORAY CO., LTD. (JP) 2024-06-06 WO disclosed
EP-3435962-B1 DEVICE FOR APPLYING A COMPOSITION IN THE FORM OF AN EMULSION COMPRISING A FILM-FORMING AGENT AND NON-VOLATILE OILS OREAL (FR) 2024-05-22 EP disclosed
CN-113164793-B Polymer blends for personal care formulations 陶氏环球技术有限责任公司 2024-05-17 CN disclosed
CN-114302933-B Low dielectric laminate 东洋纺MC株式会社 2024-05-10 CN disclosed
EP-3435963-B1 EMULSION COMPRISING A FILM-FORMING AGENT AND NON-VOLATILE OILS AND COSMETIC PROCESS OREAL (FR) 2024-05-01 EP disclosed
CN-114207068-B Polyolefin adhesive composition 东洋纺MC株式会社 2024-04-02 CN disclosed
US-20240059811-A1 MONOMER COMPOSITION AND METHOD FOR PRODUCING SAME, AND COSMETIC OR COSMETIC RAW MATERIAL INCLUDING MONOMER COMPOSITION DOW TORAY CO LTD (JP) 2024-02-22 US disclosed
US-5098981-A POLYORGANOSILOXANE CHISSO CORPORATION (JP) 1992-03-24 US disclosed
EP-0433906-A2 Thermoplastic resin and process for producing the same TOSHIBA SILICONE CO., LTD. (JP) 1991-06-26 EP disclosed
EP-0433727-A1 Silica-core silicone-shell particles, emulsion containing the same dispersed therein, and process for producing the emulsion TOSHIBA SILICONE CO., LTD. (JP) 1991-06-26 EP disclosed
EP-0349920-A2 Polyorganosiloxane Chisso Corporation (JP) 1990-01-10 EP disclosed
US-4871376-A CONTAINING COUPLING AGENT TO IMPROVE BONDING BETWEEN RESIN AND FILLER; WATERPROOFING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-03 US disclosed
CN-1035306-A The modified resin system and the method thereof that are used for coated article MINNESOTA MINING & MFG (US) 1989-09-06 CN disclosed
EP-0321230-A2 Improved resin systems for coated products, and method MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-06-21 EP disclosed
US-4211824-A CONJUGATED DIENE-VINYL NITROGEN HETEROCYCLE INTERPOLYMER ADHESIVE HONNY CHEMICALS COMPANY, LTD. (JP) 1980-07-08 US disclosed
US-4182775-A Benzoic acids and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059811-A1 MONOMER COMPOSITION AND METHOD FOR PRODUCING SAME, AND COSMETIC OR COSMETIC RAW MATERIAL INCLUDING MONOMER COMPOSITION NOTUM, CUTA, NOS1 ALDH1A1 843/4885TSHR 4724/4885TDP1 420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.