Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30205296

C[C@@H]1CN(C=O)C[C@H](C)O1.O=C(O)C(F)(F)F

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
PKM P14618 1/20 0.38
MAPK1 P28482 1/20 0.38
FKBP1A P62942 1/20 0.38
HPGD P15428 2/20 0.36
KMT2A Q03164 5/20 0.35
MEN1 O00255 2/20 0.35
SMN1; SMN2 Q16637 3/20 0.34
TSHR P16473 1/20 0.34
MAPT P10636 1/20 0.34
KDM4E B2RXH2 2/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
NPC1 O15118 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL28698717 0.83 ALDH1A1 (0.39) ALDH1A1L3MBTL1
SCHEMBL28398368 0.82 ALDH1A1 (0.46) ALDH1A1L3MBTL1PKMMAPK1FKBP1A
SCHEMBL38657611 0.82 ALDH1A1 (0.46) ALDH1A1L3MBTL1PKMMAPK1FKBP1A
SCHEMBL294985 0.82 ALDH1A1 (0.46) ALDH1A1L3MBTL1PKMMAPK1FKBP1A
SCHEMBL3647529 0.82 ALDH1A1 (0.46) ALDH1A1L3MBTL1PKMMAPK1FKBP1A
Trifluoroacetic Acid SCHEMBL28528335 0.77 ALDH1A1 (0.33) ALDH1A1L3MBTL1
Trifluoroacetic Acid SCHEMBL28709600 0.77 DPP4 (0.35) ALDH1A1L3MBTL1
SCHEMBL30997338 0.76 ALDH1A1 (0.44) ALDH1A1L3MBTL1
Trifluoroacetic Acid SCHEMBL28864591 0.74 ALDH1A1 (0.45) ALDH1A1L3MBTL1KMT2AMEN1SMN1; SMN2
Trifluoroacetic Acid SCHEMBL28709650 0.70 HSD17B10 (0.39) ALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115715289-B Polyarylate and application thereof 江苏先声药业有限公司 2024-12-03 CN disclosed
CN-115715289-A Polyarylate and use thereof 江苏先声药业有限公司 2023-02-24 CN disclosed