SCHEMBL302059

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2189008	0.94	LMNA (0.49)	LMNAMAPTKMT2AHPGDALDH1A1
	SCHEMBL3377152	0.93	LMNA (0.60)	LMNAKMT2AHPGDALDH1A1MEN1
	SCHEMBL3377105	0.87	ALDH1A1 (0.49)	LMNAKMT2AHPGDALDH1A1MEN1
	SCHEMBL2213840	0.86	TSHR (0.53)	LMNAMAPTKMT2AHPGDALDH1A1
	SCHEMBL3374237	0.85	HPGD (0.52)	LMNAKMT2AHPGDALDH1A1TSHR
	SCHEMBL2192252	0.82	LMNA (0.71)	LMNAMAPTKMT2AALDH1A1MEN1
	SCHEMBL303280	0.82	ALDH1A1 (0.44)	LMNAKMT2AHPGDALDH1A1L3MBTL1
	SCHEMBL3377040	0.82	LMNA (0.48)	LMNAKMT2AHPGDALDH1A1MEN1
	SCHEMBL303740	0.81	LMNA (0.47)	LMNAKMT2AHPGDALDH1A1MEN1
	SCHEMBL3379849	0.79	MAPT (0.59)	LMNAMAPTKMT2AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.