SCHEMBL3374237

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2213840	0.95	TSHR (0.53)	HPGDPTGESALOX5LMNAALDH1A1
	SCHEMBL303713	0.90	SLC6A12 (0.46)	HPGDPTGESALOX5LMNAALDH1A1
	SCHEMBL3436361	0.89	ALDH1A1 (0.42)	HPGDPTGESALOX5LMNAALDH1A1
	SCHEMBL3377152	0.88	LMNA (0.60)	HPGDLMNAALDH1A1TSHRKMT2A
	SCHEMBL3377040	0.85	LMNA (0.48)	HPGDLMNAALDH1A1TSHRKMT2A
	SCHEMBL302059	0.85	LMNA (0.52)	HPGDLMNAALDH1A1TSHRKMT2A
	SCHEMBL3377105	0.81	ALDH1A1 (0.49)	HPGDLMNAALDH1A1TSHRKMT2A
	SCHEMBL2189008	0.80	LMNA (0.49)	HPGDLMNAALDH1A1TSHRKMT2A
	SCHEMBL304306	0.79	LMNA (0.57)	HPGDPTGESALOX5LMNAALDH1A1
	SCHEMBL303740	0.76	LMNA (0.47)	HPGDLMNAALDH1A1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.