Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | CFD | P00746 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19655515 | 1.00 | ALOX15 (0.48) | ALOX15CHRM2CHRM1ADRB2ADRA2A | |
| SCHEMBL22733403 | 0.85 | CFD (0.52) | CHRM2CHRM1CFDCYP4F2CYP4A11 | |
| SCHEMBL30206648 | 0.82 | CFD (0.55) | ALOX15CHRM2CHRM1ADRB2ADRA2A | |
| SCHEMBL19640086 | 0.82 | CFD (0.55) | ALOX15CHRM2CHRM1ADRB2ADRA2A | |
| SCHEMBL30394978 | 0.82 | MTNR1A (0.46) | CYP4F2CYP4A11MTNR1AMTNR1BCA12 | |
| SCHEMBL19655516 | 0.80 | ALDH1A1 (0.41) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL30206796 | 0.80 | ALDH1A1 (0.41) | ALOX15ADRB2ADRA2ADRD2ADRA2C | |
| SCHEMBL31588004 | 0.76 | EGFR (0.51) | EGFRCA12CA2CA3CA6 | |
| SCHEMBL22032195 | 0.75 | EGFR (0.39) | ADRB2ADRA1ACYP4F2CYP4A11MTNR1A | |
| SCHEMBL31588092 | 0.73 | HTT (0.38) | CYP4F2CYP4A11MTNR1AMTNR1BSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415353-B | Pegylated carfilzomib compounds | 美国安进公司 | 2023-01-10 | — | — | CN | disclosed |