Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 7/20 | 0.44 |
| ▸ | RXRA | P19793 | 6/20 | 0.44 |
| ▸ | RXRG | P48443 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263606 | 0.78 | GABRA1 (0.48) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL3590702 | 0.78 | GABRA1 (0.48) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL3550108 | 0.75 | CES2 (0.56) | RXRBRXRARXRGMAPTGAA | |
| SCHEMBL501957 | 0.75 | RXRB (0.64) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL8648310 | 0.75 | SRD5A2 (0.54) | MAPTMAPK1RARBRARGPOLB | |
| SCHEMBL93161 | 0.74 | GABRA1 (0.69) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL41248 | 0.74 | GABRA1 (0.55) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL28949673 | 0.73 | POLB (0.44) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL28170145 | 0.73 | RXRB (0.62) | GABRA1GABRB2RXRBRXRARXRG | |
| SCHEMBL5873298 | 0.73 | RXRB (0.62) | GABRA1GABRB2RXRBRXRARXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115698292-A | Aptamers binding to thiamine analogs and derivatives | 梅里特斯英国第二有限公司 | 2023-02-03 | — | — | CN | disclosed |
| US-20120277420-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-11-01 | — | — | US | disclosed |
| US-8212055-B2 | Refined routes to chlorin building blocks | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-07-03 | — | — | US | disclosed |
| US-20100204465-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-08-12 | — | — | US | disclosed |
| US-7678900-B2 | Refined routes to chlorin building blocks | NORTH CAROLINA STATE UNIVERSITY (US) | 2010-03-16 | — | — | US | disclosed |
| US-20090069558-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-03-12 | — | — | US | disclosed |
| US-7470785-B2 | Refined routes to chlorin building blocks | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-12-30 | — | — | US | disclosed |
| US-6946552-B2 | Refined routes to chlorin building blocks | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-09-20 | — | — | US | disclosed |
| US-20050165228-A1 | Refined routes to chlorin building blocks | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-07-28 | — | — | US | disclosed |
| US-20030096989-A1 | Refined routes to chlorin building blocks | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-05-22 | — | — | US | disclosed |
| WO-2002092601-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069558-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | DHFR, DDT, SHARPIN | GABRA1 2685/4885GABRB2 1322/4885RXRB 1708/4885 |
| US-20050165228-A1 | Refined routes to chlorin building blocks | DHFR, DDT, SHARPIN | GABRA1 2685/4885GABRB2 1322/4885RXRB 1708/4885 |
| US-20100204465-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | DHFR, DDT, SHARPIN | GABRA1 2685/4885GABRB2 1322/4885RXRB 1708/4885 |
| US-20120277420-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | DHFR, DDT, SHARPIN | GABRA1 2685/4885GABRB2 1322/4885RXRB 1708/4885 |
| US-20030096989-A1 | Refined routes to chlorin building blocks | DHFR, DDT, SHARPIN | GABRA1 2685/4885GABRB2 1322/4885RXRB 1708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.