SCHEMBL501957

SCHEMBL501957

CC(C)(C)c1cc(C(=O)O)cc(C(C)(C)C)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRB P28702 7/20 0.64
RXRA P19793 6/20 0.64
RXRG P48443 3/20 0.64
TDP1 Q9NUW8 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
TP53 P04637 1/20 0.56
CYP3A4 P08684 1/20 0.56
MAPT P10636 1/20 0.56
ALOX15 P16050 1/20 0.56
MAPK1 P28482 1/20 0.56
BLM P54132 1/20 0.56
CASP7 P55210 1/20 0.56
HSD17B10 Q99714 1/20 0.56
SRD5A2 P31213 1/20 0.54
GABRA1 P14867 1/20 0.50
GABRB2 P47870 1/20 0.50
RARB P10826 2/20 0.48
RARG P13631 2/20 0.48
TPMT P51580 1/20 0.48
RARA P10276 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5873298 0.98 RXRB (0.62) RXRBRXRARXRGTDP1SMN1; SMN2
SCHEMBL28170145 0.98 RXRB (0.62) RXRBRXRARXRGTDP1SMN1; SMN2
SCHEMBL166878 0.95 RXRB (0.59) RXRBRXRARXRGTDP1SMN1; SMN2
Hydrochloric Acid SCHEMBL4585979 0.93 RXRB (0.57) RXRBRXRARXRGTDP1SMN1; SMN2
Hydrochloric Acid SCHEMBL11879619 0.93 RXRB (0.57) RXRBRXRARXRGTDP1SMN1; SMN2
Water SCHEMBL28383353 0.93 RXRB (0.57) RXRBRXRARXRGTDP1SMN1; SMN2
SCHEMBL15122888 0.91 RXRB (0.56) RXRBRXRARXRGTDP1SMN1; SMN2
SCHEMBL12187529 0.89 CES2 (0.57) RXRBRXRARXRGTDP1SMN1; SMN2
SCHEMBL29419323 0.87 CA12 (0.60) RXRBRXRARXRGTDP1SMN1; SMN2
SCHEMBL13043940 0.87 RXRA (0.52) RXRBRXRARXRGTDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 743 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-110669067-B Process for preparing alkylalkoxysilanes 赢创运营有限公司 2024-06-04 CN claimed
EP-3312214-B1 METHOD OF SYNTHESISING POLYCARBONATES IN THE PRESENCE OF A BIMETALLIC CATALYST AND A CHAIN TRANSFER AGENT IMPERIAL INNOVATIONS LTD (GB) 2023-08-16 EP claimed
CN-115710326-A Dibenzofuran bridged aryloxy metal complex catalyst, and method and application thereof 万华化学集团股份有限公司 2023-02-24 CN claimed
CN-108570069-B Process for preparing tris [3- (alkoxysilyl) propyl ] isocyanurate 赢创运营有限公司 2022-07-05 CN claimed
CN-108570070-B Process for preparing tris [3- (alkoxysilyl) propyl ] isocyanurate 赢创运营有限公司 2022-07-05 CN claimed
EP-4013438-A1 HERBAL PREPARATION FOR STIMULATION OF HAIR GROWTH, CONTROL OF HAIR FALL, DANDRUFF AND INFECTIONS THEREOF USING AGERATUM SPP GE Nutrients, Inc. (US) 2022-06-22 EP claimed
CN-114555104-A Herbal preparation for stimulating hair growth, controlling hair loss, dandruff and infections thereof using ageratum species GE营养有限公司 2022-05-27 CN claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
US-20040242922-A1 Method of oxidising hydrocarbons to acids RHODIA POLYMIDE INTERMEDIATES (FR) 2004-12-02 US claimed
CN-1549805-A Method of oxidising hydrocarbons to acids �޵��Ǿ������м��幫˾ 2004-11-24 CN claimed
US-6692880-B2 FOR PRINTING IMAGES HEIDELBERGER DRUCKMASCHINEN AG (DE) 2004-02-17 US claimed
US-20030073017-A1 For printing images BANK OF AMERICA, N.A., AS AGENT 2003-04-17 US claimed
EP-1293835-A2 Electrophotographic toner with stable triboelectric properties Heidelberger Druckmaschinen Aktiengesellschaft (DE) 2003-03-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 RXRB 407/4885RXRA 577/4885RXRG 570/4885
US-20040242922-A1 Method of oxidising hydrocarbons to acids ACOX1, AOC3, ACOX3 RXRB 445/4885RXRA 573/4885RXRG 669/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 RXRB 1343/4885RXRA 761/4885RXRG 1249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.