Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.82 |
| ▸ | RECQL | P46063 | 2/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | MMP2 | P08253 | 2/20 | 0.61 |
| ▸ | MMP7 | P09237 | 2/20 | 0.61 |
| ▸ | MMP14 | P50281 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202982 | 0.91 | HSD11B1 (1.00) | HSD11B1RECQLLMNAALDH1A1PKM | |
| SCHEMBL2422002 | 0.91 | RECQL (1.00) | HSD11B1RECQLLMNAALDH1A1PKM | |
| SCHEMBL29609963 | 0.89 | RECQL (0.97) | HSD11B1RECQLLMNAALDH1A1PKM | |
| SCHEMBL28392708 | 0.89 | RECQL (0.73) | HSD11B1RECQLALDH1A1MMP2MMP7 | |
| SCHEMBL16660516 | 0.89 | HSD11B1 (0.73) | HSD11B1RECQLALDH1A1MMP2MMP7 | |
| SCHEMBL29012562 | 0.89 | HSD11B1 (0.83) | HSD11B1RECQLLMNAALDH1A1PKM | |
| SCHEMBL10872654 | 0.86 | RECQL (0.91) | HSD11B1RECQLLMNAALDH1A1PKM | |
| SCHEMBL30209483 | 0.84 | HSD11B1 (0.76) | HSD11B1RECQLLMNAALDH1A1PKM | |
| SCHEMBL6199060 | 0.81 | KMT2A (0.73) | HSD11B1RECQLLMNAALDH1A1PKM | |
| SCHEMBL29012568 | 0.81 | KMT2A (0.73) | HSD11B1RECQLLMNAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978216-B | Preparation method of beta-carbonyl sulfone compound | 西南医科大学 | 2023-02-03 | — | — | CN | disclosed |