Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.46 |
| ▸ | PFKFB3 | Q16875 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30209643 | 0.82 | PFKFB3 (0.52) | HDAC6HDAC8HDAC2HDAC1PFKFB3 | |
| SCHEMBL30209650 | 0.82 | BACE1 (0.47) | HDAC6HDAC8HDAC2HDAC1PFKFB3 | |
| SCHEMBL30209657 | 0.82 | MAPT (0.52) | HDAC6HDAC8HDAC2HDAC1PFKFB3 | |
| SCHEMBL30209641 | 0.79 | HDAC8 (0.71) | HDAC6HDAC8HDAC2HDAC1PFKFB3 | |
| SCHEMBL30209665 | 0.78 | HDAC6 (0.53) | HDAC6HDAC8HDAC2HDAC1PFKFB3 | |
| SCHEMBL30209647 | 0.78 | PFKFB3 (0.55) | HDAC6HDAC8HDAC2HDAC1PFKFB3 | |
| SCHEMBL5717629 | 0.78 | LMNA (0.73) | HDAC6HDAC8HDAC2HDAC1PFKFB3 | |
| SCHEMBL30209642 | 0.78 | LMNA (0.73) | HDAC6HDAC8HDAC2HDAC1PFKFB3 | |
| SCHEMBL5717630 | 0.78 | LMNA (0.73) | HDAC6HDAC8HDAC2HDAC1PFKFB3 | |
| SCHEMBL13456148 | 0.75 | CCR1 (0.47) | HDAC6HDAC8HDAC2HDAC1PFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745898-A | Aromatic acrylamide-triazole compound, and preparation method and application thereof | 许昌学院 | 2023-03-07 | — | — | CN | disclosed |