Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28980463 | 0.86 | KDM4E (0.62) | MAPTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL30209643 | 0.82 | PFKFB3 (0.52) | MAPTMEN1KMT2AALDH1A1HDAC6 | |
| SCHEMBL30209652 | 0.82 | HDAC6 (0.46) | MAPTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL30209650 | 0.82 | BACE1 (0.47) | MAPTALDH1A1L3MBTL1HDAC6HDAC2 | |
| SCHEMBL30209641 | 0.79 | HDAC8 (0.71) | MAPTMEN1KMT2AALDH1A1HDAC6 | |
| SCHEMBL30209665 | 0.78 | HDAC6 (0.53) | MAPTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL30209647 | 0.78 | PFKFB3 (0.55) | MAPTALDH1A1HDAC6HDAC2HDAC1 | |
| SCHEMBL19511084 | 0.78 | KDM4E (0.49) | MAPTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL30350579 | 0.78 | KDM4E (0.49) | MAPTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL5717629 | 0.78 | LMNA (0.73) | MAPTMEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745898-A | Aromatic acrylamide-triazole compound, and preparation method and application thereof | 许昌学院 | 2023-03-07 | — | — | CN | disclosed |