SCHEMBL30211024

SCHEMBL30211024

CC[Si](CC)(CC)c1ccc2c(c1)Cc1cc([Si](CC)(CC)CC)ccc1-2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.41
NPC1 O15118 3/20 0.39
MAPT P10636 2/20 0.39
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
HSD17B1 P14061 1/20 0.34
KMT2A Q03164 2/20 0.33
TSHR P16473 1/20 0.33
ATM Q13315 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP1A2 P05177 3/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4890413 1.00 RAB9A (0.41) RAB9ANPC1MAPTALDH1A1KDM4E
SCHEMBL4895487 0.87 NR1H2 (0.34) RAB9ANPC1MAPTALDH1A1KDM4E
SCHEMBL30211013 0.77 RAB9A (0.42) RAB9ANPC1MAPTALDH1A1KDM4E
SCHEMBL4354370 0.76 RAB9A (0.37) RAB9ANPC1MAPTALDH1A1KDM4E
SCHEMBL25470451 0.72 MAPT (0.38) RAB9ANPC1MAPTALDH1A1KDM4E
SCHEMBL10357234 0.71 METAP1 (0.46) RAB9ANPC1MAPTALDH1A1KDM4E
SCHEMBL4900295 0.71 NR1H2 (0.39) RAB9ANPC1MAPTALDH1A1KDM4E
SCHEMBL7056361 0.69 NR1H2 (0.54) NR1H2NR1H3ESR1ESR2
SCHEMBL4894905 0.68 ALDH1A1 (0.46) RAB9ANPC1MAPTALDH1A1KDM4E
SCHEMBL13138273 0.68 ALDH1A1 (0.42) RAB9ANPC1MAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677879-B Catalyst for preparing cycloolefin copolymer, preparation method of cycloolefin copolymer, cycloolefin copolymer and application of cycloolefin copolymer 华为技术有限公司 2024-07-30 CN disclosed
CN-115677879-A Catalyst for preparing cycloolefin copolymer, preparation method of cycloolefin copolymer, cycloolefin copolymer and application of cycloolefin copolymer 华为技术有限公司 2023-02-03 CN disclosed