SCHEMBL4895487

SCHEMBL4895487

CC[Si](CC)(CC)c1ccc2c(c1)-c1cc([Si](CC)(CC)CC)ccc1C2

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
RAB9A P51151 4/20 0.33
MAPT P10636 3/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33
GABRA4 P48169 1/20 0.33
GABRE P78334 1/20 0.33
GABRA6 Q16445 1/20 0.33
GABRG1 Q8N1C3 1/20 0.33
GABRG3 Q99928 1/20 0.33
GABRQ Q9UN88 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30211024 0.87 RAB9A (0.41) NR1H2NR1H3RAB9AMAPTNPC1
SCHEMBL4890413 0.87 RAB9A (0.41) NR1H2NR1H3RAB9AMAPTNPC1
SCHEMBL4899752 0.77 MAPT (0.35) NR1H2NR1H3RAB9AMAPTNPC1
SCHEMBL25470451 0.72 MAPT (0.38) RAB9AMAPTNPC1ALDH1A1KDM4E
SCHEMBL4899827 0.71 NR1H2 (0.39) NR1H2NR1H3MAPT
SCHEMBL7056361 0.69 NR1H2 (0.54) NR1H2NR1H3ESR1ARESR2
SCHEMBL4896965 0.68 ALDH1A1 (0.45) RAB9AMAPTNPC1ALDH1A1KDM4E
SCHEMBL12879656 0.68 KDM4E (0.38) RAB9AMAPTNPC1ALDH1A1KDM4E
SCHEMBL12219219 0.68 KDM4E (0.38) RAB9AMAPTNPC1ALDH1A1KDM4E
SCHEMBL12879690 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8084559-B2 Ethylene-vinylcyclohexane copolymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-27 US disclosed
US-20080161514-A1 Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer SUMITOMO CHEMICAL COMPANY, LIMTIED (JP) 2008-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161514-A1 Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer AOC2, ACSL1, ACSL3 NR1H2 105/4885NR1H3 94/4885RAB9A 1868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.