SCHEMBL30211367

SCHEMBL30211367

Brc1ccc2c(c1)SCO2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.46
BLM P54132 2/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
HTT P42858 1/20 0.42
BACE1 P56817 3/20 0.33
CYP1A2 P05177 2/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
CYP2C19 P33261 1/20 0.32
CA2 P00918 2/20 0.32
APP P05067 2/20 0.32
CYP19A1 P11511 1/20 0.32
MAOB P27338 2/20 0.32
PBRM1 Q86U86 1/20 0.32
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16042250 1.00 AHR (0.46) AHRBLMLMNAMAPTHTT
SCHEMBL24988229 0.83 BLM (0.42) AHRBLMLMNAMAPTHTT
SCHEMBL20741917 0.80 LMNA (0.48) AHRBLMLMNAMAPTHTT
SCHEMBL3356952 0.75 MAPT (0.39) MAPTHTTCYP1A2CASP1CA2
SCHEMBL5545052 0.75 TUBB4A (0.33) SLC5A2
SCHEMBL11209169 0.75 CYP3A4 (0.47) MAPTHPGDMAOBCYP3A4SLC5A2
SCHEMBL13975336 0.75 SLC5A2 (0.31) SLC5A2
SCHEMBL8930712 0.74 TUBB4A (0.35)
SCHEMBL11392234 0.71 ALDH1A1 (0.52) TSHRTDP1
SCHEMBL15911961 0.71 PARP1 (0.41) LMNAMAPTCYP1A2SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370114-A2 NOVEL SHORT-ACTING PSYCHOACTIVE COMPOUNDS OF THE MDMA CLASS Mydecine Innovations Group Inc. (US) 2024-05-22 EP disclosed
WO-2023288013-A2 NOVEL SHORT-ACTING PSYCHOACTIVE COMPOUNDS OF THE MDMA CLASS MYDECINE INNOVATIONS GROUP INC. (US) 2023-01-19 WO disclosed