Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17361319 | 0.96 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8204708 | 0.87 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL5090074 | 0.87 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL3021167 | 0.86 | CA12 (0.60) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL15941551 | 0.83 | CA12 (0.60) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8551794 | 0.82 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8373486 | 0.81 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL3113016 | 0.81 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8374769 | 0.81 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8549614 | 0.81 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210694-A1 | NEW NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-08-19 | — | — | US | disclosed |
| US-20100210694-A1 | NEW NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210694-A1 | NEW NO-DONOR ASPIRIN DERIVATIVES | PTGIS, NOS2, NOS3 | ALDH1A1 245/4885SMN1; SMN2 4131/4885MAPT 4568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.