Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14820155 | 0.75 | HTR1A (0.31) | — | |
| SCHEMBL10334519 | 0.75 | CYP3A4 (0.35) | CYP3A4CYP2C9 | |
| SCHEMBL18484525 | 0.71 | — | — | |
| SCHEMBL18487515 | 0.71 | — | — | |
| SCHEMBL3170197 | 0.70 | POLB (0.57) | RAB9ANPC1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2177739 | 0.69 | SMN1; SMN2 (0.61) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL10989704 | 0.67 | RAB9A (0.40) | RAB9ASMN1; SMN2ALDH1A1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL30211804 | 0.67 | MEN1 (0.43) | RAB9ANPC1TDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11520651 | 0.62 | ALDH1A1 (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL27557283 | 0.61 | CA2 (0.46) | NPSR1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697334-A | Methods of improving retinal related disease outcomes using CCR3 inhibitors | 万能溶剂有限公司 | 2023-02-03 | — | — | CN | disclosed |