Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 15/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 13/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30212204 | 0.77 | NOTUM (0.54) | NPBWR1MCHR1PTPN1EGLN1 | |
| SCHEMBL20912238 | 0.75 | EGLN1 (0.39) | EGLN1 | |
| SCHEMBL24922678 | 0.74 | NPBWR1 (0.37) | NPBWR1MCHR1EGLN1FGFR2 | |
| SCHEMBL15849015 | 0.72 | ALDH1A1 (0.48) | PTPN1 | |
| SCHEMBL4366979 | 0.72 | ALDH1A1 (0.48) | PTPN1 | |
| SCHEMBL12261859 | 0.70 | PTPN1 (0.39) | NPBWR1MCHR1PTPN1FGFR2 | |
| SCHEMBL5018912 | 0.69 | TDP1 (0.56) | — | |
| SCHEMBL12261854 | 0.69 | KDM4C (0.40) | NPBWR1MCHR1PTPN1FGFR2 | |
| SCHEMBL24920613 | 0.68 | ACACB (0.37) | — | |
| SCHEMBL17572221 | 0.68 | NPBWR1 (0.41) | NPBWR1MCHR1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |