Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MECP2 | P51608 | 1/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6334778 | 1.00 | MAP4K4 (0.50) | MAP4K4MEN1KDM4EALDH1A1MAPT | |
| SCHEMBL17984217 | 0.79 | GP6 (0.44) | MAOALRRK2NPC1RAB9AKAT6A | |
| SCHEMBL4325008 | 0.78 | NOTUM (0.46) | LRRK2KAT6A | |
| SCHEMBL1545373 | 0.78 | IDO1 (0.46) | MEN1MAPTKMT2ANPC1GLA | |
| SCHEMBL13466167 | 0.78 | MEN1 (0.50) | MEN1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL31010202 | 0.78 | RAB9A (0.49) | MEN1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL12457 | 0.78 | RAB9A (0.49) | MEN1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL29930074 | 0.78 | MEN1 (0.50) | MEN1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL70247 | 0.76 | RAB9A (0.48) | MEN1KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL30207 | 0.76 | PPARA (0.46) | NPC1RAB9AKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119591596-A | 4, 5-Dihydro-3H-pyrrolo [2,3-c ] quinolin-4-one derivatives and uses thereof | 沈阳药科大学 | 2025-03-11 | — | — | CN | disclosed |
| CN-119504808-A | Compound, preparation method and application thereof | 四川科伦药物研究院有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-119241539-A | Pyrazolo piperidine (ketone) -containing derivative, and preparation method and application thereof | 沈阳药科大学 | 2025-01-03 | — | — | CN | disclosed |
| CN-115697974-A | Imidazole 3-oxide derivative based ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2023-02-03 | — | — | CN | disclosed |