SCHEMBL3021332

SCHEMBL3021332

CCCCC(=O)O[C@]1(C(=O)COC(C)=O)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 9/20 0.83
▸ CYP3A4 P08684 5/20 0.83
▸ PGR P06401 5/20 0.83
▸ USP2 O75604 3/20 0.83
▸ MEN1 O00255 1/20 0.83
▸ KMT2A Q03164 1/20 0.83
▸ NR1I2 O75469 2/20 0.80
▸ MAPT P10636 2/20 0.80
▸ ADORA3 P0DMS8 1/20 0.80
▸ DRD2 P14416 1/20 0.80
▸ OPRD1 P41143 1/20 0.80
▸ LMNA P02545 3/20 0.72
▸ HIF1A Q16665 3/20 0.72
▸ SMN1; SMN2 Q16637 3/20 0.72
▸ CYP2C9 P11712 2/20 0.72
▸ CNR1 P21554 1/20 0.72
▸ TBXA2R P21731 1/20 0.72
▸ MLNR O43193 1/20 0.71
▸ ABCB11 O95342 1/20 0.71
▸ CYP3A5 P20815 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29438083 1.00 NR3C1 (0.83) NR3C1CYP3A4PGRUSP2MEN1
SCHEMBL10797796 0.96 NR3C1 (0.81) NR3C1CYP3A4PGRUSP2MEN1
SCHEMBL10797800 0.96 NR3C1 (0.81) NR3C1CYP3A4PGRUSP2MEN1
SCHEMBL10797802 0.96 NR3C1 (0.81) NR3C1CYP3A4PGRUSP2MEN1
SCHEMBL4888415 0.95 NR3C1 (0.86) NR3C1CYP3A4PGRUSP2MEN1
SCHEMBL3021328 0.95 NR3C1 (0.81) NR3C1CYP3A4PGRUSP2MEN1
SCHEMBL14867458 0.95 NR3C1 (0.84) NR3C1CYP3A4PGRUSP2MEN1
SCHEMBL10866655 0.94 NR3C1 (0.83) NR3C1CYP3A4PGRUSP2MEN1
SCHEMBL11520052 0.94 NR3C1 (0.90) NR3C1CYP3A4PGRUSP2MEN1
SCHEMBL10866663 0.94 NR3C1 (0.83) NR3C1CYP3A4PGRUSP2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11660268-B2 Emulsified gel composition HISAMITSU PHARMACEUTICAL CO.. INC. (JP) 2023-05-30 — — US disclosed
WO-2023017790-A1 CLEANING COMPOSITION AND PRODUCTION METHOD FOR SAME ロート製薬株式会社 2023-02-16 — — WO disclosed
CN-111787953-B Emulsified gel composition 久光制药株式会社 2022-12-09 — — CN disclosed
US-11246830-B2 Emulsified gel composition HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2022-02-15 — — US disclosed
US-11219601-B2 — — 2022-01-11 — — US disclosed
EP-3760231-A1 EMULSIFIED GEL COMPOSITION Hisamitsu Pharmaceutical Co., Inc. (JP) 2021-01-06 — — EP disclosed
US-20200397694-A1 EMULSIFIED GEL COMPOSITION HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2020-12-24 — — US disclosed
CN-111787953-A Emulsified gel composition 久光制药株式会社 2020-10-16 — — CN disclosed
US-20200138695-A1 COSMETIC COMPOSITION ROHTO PHARMACEUTICAL CO., LTD. (JP) 2020-05-07 — — US disclosed
EP-3616683-A1 COSMETIC COMPOSITION Rohto Pharmaceutical Co., Ltd. (JP) 2020-03-04 — — EP disclosed
US-20150202243-A1 HDC Activation Inhibitor, HDC Activation Inhibition Composition, Antipruritic Agent, and Antipruritic Agent Composition HOYU CO., LTD. (JP) 2015-07-23 — — US disclosed
CN-101754765-B Emulsion compositions ROHTO PHARMA 2013-04-17 — — CN disclosed
CN-102008729-A Composition for external use ROHTO PHARMA 2011-04-13 — — CN disclosed
US-20100209364-A1 Emulsified Composition ROHTO PHARMACEUTICAL CO., LTD. (JP) 2010-08-19 — — US disclosed
CN-101754765-A emulsion compositions ROHTO PHARMA 2010-06-23 — — CN disclosed
US-20100021405-A1 EXTERNAL PREPARATION FOR SKIN ROHTO PHARMACEUTICAL CO., LTD. (JP) 2010-01-28 — — US disclosed
CN-101534862-A External preparation for skin ROHTO PHARMA (JP) 2009-09-16 — — CN disclosed
US-20080207560-A1 Composition For External Use ROHTO PHARMACEUTICAL CO., LTD. (JP) 2008-08-28 — — US disclosed
CN-101102797-A External composition ROHTO PHARMA (JP) 2008-01-09 — — CN disclosed
EP-1849481-A1 COMPOSITION FOR EXTERNAL USE ROHTO PHARMACEUTICAL CO., LTD. (JP) 2007-10-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200138695-A1 COSMETIC COMPOSITION CUTA, LAGE3, SMURF1 NR3C1 4161/4885CYP3A4 4824/4885PGR 951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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