Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.41 |
| ▸ | TUBB | P07437 | 4/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4908473 | 1.00 | ENPP2 (0.52) | ENPP2TDP1KDM4EERN1TUBB4A | |
| SCHEMBL1235272 | 0.83 | ENPP2 (0.52) | ENPP2TDP1KDM4ETUBB4ATUBB | |
| SCHEMBL12004570 | 0.77 | MAOA (0.40) | ENPP2TDP1MEN1LMNAMAPT | |
| SCHEMBL15019984 | 0.77 | CFD (0.46) | TDP1KDM4EMEN1LMNAMAPT | |
| SCHEMBL30214860 | 0.77 | MAOA (0.40) | ENPP2TDP1MEN1LMNAMAPT | |
| SCHEMBL25173988 | 0.77 | ENPP2 (0.54) | ENPP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL203357 | 0.77 | CA1 (0.58) | ENPP2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1228414 | 0.77 | ACHE (0.58) | ENPP2ERN1TUBB4ATUBBTUBA3C | |
| SCHEMBL29955197 | 0.77 | ACHE (0.58) | ENPP2ERN1TUBB4ATUBBTUBA3C | |
| SCHEMBL29496939 | 0.77 | CA1 (0.58) | ENPP2TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392414-A1 | INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023028534-A1 | INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |