Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21045641 | 1.00 | TRPC6 (1.00) | TRPC6 | |
| SCHEMBL21081281 | 1.00 | TRPC6 (1.00) | TRPC6 | |
| SCHEMBL30387543 | 1.00 | TRPC6 (1.00) | TRPC6 | |
| SCHEMBL21045643 | 1.00 | TRPC6 (1.00) | TRPC6 | |
| SCHEMBL21081184 | 1.00 | TRPC6 (1.00) | TRPC6 | |
| SCHEMBL26458562 | 0.91 | TRPC6 (0.83) | TRPC6 | |
| SCHEMBL26458560 | 0.91 | TRPC6 (0.83) | TRPC6 | |
| SCHEMBL30387796 | 0.89 | TRPC6 (1.00) | TRPC6 | |
| SCHEMBL21045821 | 0.89 | TRPC6 (1.00) | TRPC6 | |
| SCHEMBL21045913 | 0.88 | TRPC6 (1.00) | TRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230149393-A1 | INHIBITORS OF TRPC6 FOR TREATING RESPIRATORY CONDITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-05-18 | — | — | US | claimed |
| EP-3700902-B1 | INHIBITORS OF TRPC6 | BOEHRINGER INGELHEIM INT (DE) | 2023-03-08 | — | — | EP | claimed |
| EP-4103245-B1 | ADMINISTRATION OF CALCIUM CHANNEL TRPC6 INHIBITORS USING BALLOONS, STENTS OR OTHER MEDICAL DEVICES | KLINIKUM DER TECHNISCHEN UNIV MUENCHEN TUM KLINIKUM (DE) | 2026-04-01 | — | — | EP | disclosed |
| US-20250057829-A1 | INHIBITORS OF TRPC6 FOR TREATING FOCAL SEGMENTAL GLOMERULOSCLEROSIS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-02-20 | — | — | US | disclosed |
| US-20240408087-A1 | TRPC6 INHIBITORY COMPOUNDS FOR TREATING SEPSIS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-12-12 | — | — | US | disclosed |
| US-RE49699-E1 | Inhibitors of TRPC6 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-10-17 | — | — | US | disclosed |
| US-20230149393-A1 | INHIBITORS OF TRPC6 FOR TREATING RESPIRATORY CONDITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-05-18 | — | — | US | disclosed |
| US-20230137816-A1 | ADMINISTRATION OF CALCIUM CHANNEL TRPC6 INHIBITORS USING BALLOONS, STENTS OR OTHER MEDICAL DEVICES | DEUTSCHES HERZZENTRUM MUENCHEN DES FREISTAATES BAYERN (DE) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230137816-A1 | ADMINISTRATION OF CALCIUM CHANNEL TRPC6 INHIBITORS USING BALLOONS, STENTS OR OTHER MEDICAL DEVICES | TRPC6, TRPC1, ORAI1 | TRPC6 1/4885 |
| US-20230149393-A1 | INHIBITORS OF TRPC6 FOR TREATING RESPIRATORY CONDITIONS | TRPC6, TRPV6, NHERF1 | TRPC6 1/4885 |
| US-20240408087-A1 | TRPC6 INHIBITORY COMPOUNDS FOR TREATING SEPSIS | TRPC6, TRPC1, TRPC3 | TRPC6 1/4885 |
| US-20250057829-A1 | INHIBITORS OF TRPC6 FOR TREATING FOCAL SEGMENTAL GLOMERULOSCLEROSIS | TRPC6, REN, TRPC1 | TRPC6 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.