Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NQO1 | P15559 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005054 | 0.76 | GAA (0.57) | MAOBCA12CA9ALDH1A1GAA | |
| SCHEMBL30214941 | 0.73 | NQO1 (0.72) | NFKB1NFKB2RELAMAOBCA12 | |
| SCHEMBL9444753 | 0.73 | EYA3 (0.68) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL25389945 | 0.71 | PTPN1 (0.48) | NFKB1NFKB2RELAALDH1A1MAPT | |
| SCHEMBL5145314 | 0.70 | ALDH1A1 (0.46) | MAOBCA12CA9SMN1; SMN2ALDH1A1 | |
| SCHEMBL11494134 | 0.70 | KDM4E (0.62) | MAOBSMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL5562068 | 0.70 | MAPT (0.58) | CA12CA9SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6338103 | 0.69 | EYA3 (0.71) | — | |
| SCHEMBL8663287 | 0.69 | GAA (0.53) | CA12CA9SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL18010449 | 0.68 | KDM4E (0.65) | NFKB1NFKB2RELACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023027654-A1 | CARBOXYLIC ACID HYDRAZIDE-COUMARINE HYBRID COMPOUNDS ANTIINFLAMMATORY AND ANTICONVULSANE AGENT | CUKUROVA UNIVERSITESI REKTORLUGU (TR) | 2023-03-02 | — | — | WO | disclosed |