SCHEMBL30215

SCHEMBL30215

C=CC(O)C=C(C)C(N)=O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32
FGFR4 P22455 1/20 0.32
LMNA P02545 1/20 0.30
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35840 0.79 ALDH1A1 (0.33) ALDH1A1
SCHEMBL3268310 0.79 ALDH1A1 (0.33) ALDH1A1
SCHEMBL11878863 0.79 ALDH1A1 (0.33) ALDH1A1
SCHEMBL6530072 0.77 ALDH1A1 (0.38) TDP1ALDH1A1TSHRFGFR4LMNA
SCHEMBL27631768 0.77 TDP1 (0.36) TDP1ALDH1A1TSHRFGFR4LMNA
SCHEMBL531565 0.77 ALDH1A1 (0.38) TDP1ALDH1A1TSHRFGFR4LMNA
Hydrochloric Acid SCHEMBL6419361 0.76 ALDH1A1 (0.36) TDP1ALDH1A1TSHRFGFR4
SCHEMBL5708939 0.76 TDP1 (0.35) TDP1ALDH1A1TSHRFGFR4
SCHEMBL9772444 0.75 LMNA (0.37) TDP1LMNAALOX15BLMPMP22
SCHEMBL27789841 0.74 ALDH1A1 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 751 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118043077-A Drug-loaded single-molecule nano polymer, prodrug, micelle, drug delivery system, preparation method and application 嘉兴清准医药科技有限公司 2024-05-14 CN claimed
CN-117500822-A Polynucleotide capable of enhancing protein expression and use thereof 生物欧赛加有限责任公司 2024-02-02 CN claimed
CN-114983926-B Detachable soluble microneedle for promoting skin and hair regeneration and preparation method thereof 南方医科大学南方医院 2024-01-26 CN claimed
CN-112153957-B Use of microneedle patch for promoting hair growth 北卡罗来纳州立大学 2023-12-26 CN claimed
CN-116981484-A Use of miRNA-485 inhibitor to regulate expression of PSD95, synaptorin and caspase 3 生物欧赛加有限责任公司 2023-10-31 CN claimed
CN-116963722-A Micelle nanoparticle and use thereof 生物欧赛加有限责任公司 2023-10-27 CN claimed
CN-116963755-A Modified interleukin 2 (IL-2) polypeptides and methods of making and using the same 赛缇姆治疗公司 2023-10-27 CN claimed
CN-116963785-A Use of miRNA-485 inhibitors for treating diseases or conditions associated with aberrant NLRP3 expression 生物欧赛加有限责任公司 2023-10-27 CN claimed
CN-112638348-B Method and composition for stabilizing nanogels and dental compositions produced from nanogels 登士柏希罗纳有限公司 2023-10-24 CN claimed
CN-116829132-A Micelle nanoparticle and use thereof 生物欧赛加有限责任公司 2023-09-29 CN claimed
US-7053150-B2 Segmented polymers and their conjugates NEKTAR THERAPEUTICS AL, CORPORATION (US) 2006-05-30 US claimed
WO-2005058367-A2 PEGYLATED SMALL MOLECULES NEKTAR THERAPEUTICS AL, CORPORATION (US) 2005-06-30 WO claimed
US-20050136031-A1 Drugs covalently attached to a water-soluble oligomer; reduced first pass effect; e.g. non-opioid antagonist conjugated to a polyethylene glycol (PEG) group such as PEG-naloxol REDHILL BIOPHARMA LTD. (IL) 2005-06-23 US claimed
US-6855744-B2 Gelcasting polymeric precursors for producing net-shaped graphites UT-BATTELLE, LLC (US) 2005-02-15 US claimed
US-20040236015-A1 Segmented polymers and their conjugates NEKTAR THERAPEUTICS 2004-11-25 US claimed
US-6491891-B1 MOLDING CERAMIC POWDERS IN THE PRESENCE OF POLYMER BLENDS AS BINDERS, TO FORM CARBON COMPOSITES HAVING HIGH DENSITY, STRENGTH, THERMOCONDUCTIVITY, FRICTION, HEAT AND WEAR RESISTANCE UT-BATTELLE, INC. 2002-12-10 US claimed
EP-0465302-B1 Precursors of isocyanurate polymers having hydroxyl, urethane, isocyanate or acrylate groups, and process for their preparation ATOCHEM ELF SA (FR) 1994-12-28 EP claimed
US-4411987-A SILVER HALIDE EMULSION CONTAINING GLYCOLURIL COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1983-10-25 US claimed
US-4101461-A Method for preparation of anion exchangers by substitution of hydrophilic polymeric gels CZECHOSLOVENSKA AKADEMIE VED (CS) 1978-07-18 US claimed
US-3991018-A Method for preparation of cation exchangers by substitution of hydrophilic polymeric gels of crosslinked hydroxyalkyl acrylates and hydroxyalkylacrylamides CESKOSLOVENSKA AKADEMIE VED (CS) 1976-11-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050136031-A1 Drugs covalently attached to a water-soluble oligomer; reduced first pass effect; e.g. non-opioid antagonist conjugated to a polyethylene glycol (PEG) group such as PEG-naloxol OPRM1, OPRL1, OPRK1 TDP1 4453/4885ALDH1A1 1511/4885TSHR 2306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.