Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 9/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23980935 | 1.00 | CYP11B1 (0.39) | CYP11B1CYP11B2HTR2AHTR2CHTR2B | |
| SCHEMBL29924349 | 0.90 | HTR2A (0.37) | CYP11B1CYP11B2HTR2AHTR2CHTR2B | |
| SCHEMBL24186456 | 0.90 | HTR2A (0.37) | CYP11B1CYP11B2HTR2AHTR2CHTR2B | |
| SCHEMBL23980833 | 0.90 | HTR2A (0.37) | CYP11B1CYP11B2HTR2AHTR2CHTR2B | |
| SCHEMBL30680708 | 0.88 | MAP3K14 (0.38) | HTR2AHTR2CHTR2BNPC1HPGD | |
| SCHEMBL29924775 | 0.82 | MAPT (0.44) | HTR2AHTR2CHTR2BNPC1HPGD | |
| SCHEMBL28949266 | 0.81 | ADRA2A (0.52) | CYP11B1CYP11B2HTR2AHTR2CHTR2B | |
| SCHEMBL30217488 | 0.81 | ADRA2A (0.52) | CYP11B1CYP11B2HTR2AHTR2CHTR2B | |
| SCHEMBL30680666 | 0.80 | MAP3K14 (0.41) | HTR2AHTR2CHTR2BNPC1HPGD | |
| SCHEMBL23980818 | 0.80 | LTA4H (0.40) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143183-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |