Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | APOL1 | O14791 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30008443 | 0.92 | CHRNA7 (0.38) | FAAHSMN1; SMN2CHRNA7APOL1USP2 | |
| SCHEMBL30218353 | 0.85 | SMN1; SMN2 (0.38) | FAAHSMN1; SMN2CHRNA7APOL1KDM4E | |
| SCHEMBL30218286 | 0.83 | POLB (0.36) | FAAHCHRNA7MAPK14 | |
| SCHEMBL30218349 | 0.82 | CHRNA7 (0.36) | FAAHCHRNA7MAPK13MAPK12MAPK11 | |
| SCHEMBL30218302 | 0.81 | PARP1 (0.34) | — | |
| SCHEMBL10181075 | 0.73 | ALOX15 (0.41) | ALOX15KDM4EALDH1A1 | |
| SCHEMBL28974924 | 0.73 | APOL1 (0.49) | APOL1 | |
| SCHEMBL30218351 | 0.72 | POLB (0.37) | FAAHCHRNA7MAPK13MAPK12MAPK11 | |
| SCHEMBL9221817 | 0.68 | ALOX15 (0.47) | FAAHALOX15GSK3BKDM4EALDH1A1 | |
| SCHEMBL2003095 | 0.67 | ALOX15 (0.51) | FAAHALOX15KDM4EMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867532-A | Inhibitors of APOL1 and uses thereof | 弗特克斯药品有限公司 | 2023-03-28 | — | — | CN | disclosed |