Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | ACLY | P53396 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30008443 | 0.91 | CHRNA7 (0.38) | POLBCHRNA7FAAHMAPK14ACLY | |
| SCHEMBL30218349 | 0.88 | CHRNA7 (0.36) | POLBCHRNA7FAAHMAPK14ACLY | |
| SCHEMBL30218352 | 0.83 | FAAH (0.35) | CHRNA7FAAHMAPK14 | |
| SCHEMBL30218302 | 0.81 | PARP1 (0.34) | POLBLMNA | |
| SCHEMBL30218351 | 0.79 | POLB (0.37) | POLBCHRNA7FAAHMAPK14ACLY | |
| SCHEMBL30218353 | 0.77 | SMN1; SMN2 (0.38) | POLBCHRNA7FAAH | |
| SCHEMBL19543201 | 0.71 | ACHE (0.39) | POLBACLYLMNA | |
| SCHEMBL9221170 | 0.64 | ACLY (0.50) | FAAHACLYLMNA | |
| SCHEMBL28628728 | 0.64 | LMNA (0.43) | POLBLMNA | |
| SCHEMBL10180980 | 0.63 | KMT2A (0.39) | POLBACLYLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867532-A | Inhibitors of APOL1 and uses thereof | 弗特克斯药品有限公司 | 2023-03-28 | — | — | CN | disclosed |