Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15000837 | 0.88 | MEN1 (0.46) | MMP2MMP1MMP8MMP13CA1 | |
| SCHEMBL1844913 | 0.86 | MEN1 (0.42) | MMP2MMP1MMP8MMP13CA1 | |
| SCHEMBL19809912 | 0.81 | L3MBTL1 (0.45) | MMP2MMP1MMP8MMP13CA1 | |
| SCHEMBL27852260 | 0.81 | TSHR (0.47) | MMP2MMP1MMP8MMP13CA1 | |
| SCHEMBL1258986 | 0.81 | STAT3 (0.47) | MMP2MMP1MMP8MMP13CA1 | |
| SCHEMBL29259800 | 0.81 | NPC1 (0.46) | MMP2MMP1MMP8MMP13CA1 | |
| SCHEMBL11249350 | 0.81 | PLCG1 (0.45) | MMP2MMP1MMP8MMP13CA1 | |
| SCHEMBL30555660 | 0.80 | PARL (0.44) | MMP2MMP1MMP8MMP13CA1 | |
| SCHEMBL3447513 | 0.80 | PARL (0.44) | MMP2MMP1MMP8MMP13CA1 | |
| SCHEMBL6114697 | 0.79 | MEN1 (0.46) | MMP2MMP1MMP8MMP13CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500804-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2328619-A2 | POLYMERIC BENZYL CARBONATE-DERIVATIVES | Baxter International Inc. (US) | 2011-06-08 | — | — | EP | claimed |
| WO-2010022320-A2 | POLYMERIC BENZYL CARBONATE-DERIVATIVES | BAXTER INTERNATIONAL INC. (US) | 2010-02-25 | — | — | WO | claimed |
| US-20100048483-A1 | POLYMERIC BENZYL CARBONATE-DERIVATIVES | BAXTER HEALTHCARE S.A. (CH) | 2010-02-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048483-A1 | POLYMERIC BENZYL CARBONATE-DERIVATIVES | SI, SLC1A5, BCAT1 | MMP2 1252/4885MMP1 2196/4885MMP8 2959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.