3-(2-Bromoacetyl)-Coumarin

3-(2-Bromoacetyl)-Coumarin

SCHEMBL3022073

O=C(CBr)c1cc2ccccc2oc1=O

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.68
MAOB P27338 4/20 0.66
CA12 O43570 4/20 0.66
CA9 Q16790 4/20 0.66
TSHR P16473 3/20 0.66
CA1 P00915 1/20 0.66
CA3 P07451 1/20 0.66
CA4 P22748 1/20 0.66
CA6 P23280 1/20 0.66
CA5A P35218 1/20 0.66
CA7 P43166 1/20 0.66
GPR35 Q9HC97 1/20 0.66
CA14 Q9ULX7 1/20 0.66
CA5B Q9Y2D0 1/20 0.66
KDM4E B2RXH2 5/20 0.64
CYP1A2 P05177 2/20 0.64
NT5E P21589 1/20 0.64
MEN1 O00255 4/20 0.62
KMT2A Q03164 4/20 0.62
ALDH1A1 P00352 5/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-(2-Bromoacetyl)-Coumarin SCHEMBL30633043 1.00 LMNA (0.68) LMNAMAOBCA12CA9TSHR
3-(2-Bromoacetyl)-Coumarin SCHEMBL28782184 0.95 KDM4E (0.68) LMNAMAOBCA12CA9TSHR
3-(2-Bromoacetyl)-Coumarin SCHEMBL28678576 0.94 LMNA (0.70) LMNAMAOBCA12CA9TSHR
SCHEMBL15842724 0.84 LMNA (0.68) LMNAMAOBCA12CA9TSHR
SCHEMBL7349348 0.84 LMNA (0.78) LMNAMAOBCA12CA9TSHR
SCHEMBL26656965 0.84 LMNA (0.68) LMNAMAOBCA12CA9TSHR
Hydrochloric Acid SCHEMBL28525822 0.83 LMNA (0.67) LMNAMAOBCA12CA9TSHR
SCHEMBL20525255 0.82 KDM4E (0.72) LMNAMAOBCA12CA9TSHR
SCHEMBL15842848 0.81 GPR35 (0.47) LMNAMAOBCA12CA9TSHR
SCHEMBL28690050 0.81 MAOA (0.68) MAOBCA12CA9TSHRCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034227-A1 AZLACTONE-BASED POLYMERS AS A SCAFFOLD FOR DIVERSE APPLICATIONS IN DRUG AND GENE DELIVERY UNIV MISSISSIPPI (US) 2026-02-05 US claimed
WO-2024020355-A2 AZLACTONE-BASED POLYMERS AS A SCAFFOLD FOR DIVERSE APPLICATIONS IN DRUG AND GENE DELIVERY UNIVERSITY OF MISSISSIPPI (US) 2024-01-25 WO claimed
CN-116693466-A Gallic acid derivative containing thiazole structure and synthesis method and application thereof 江苏海洋大学 2023-09-05 CN claimed
CN-115850257-A Synthetic method of emodin amide derivatives containing coumarin thiazole and application of emodin amide derivatives in resisting marine vibrio 江苏海洋大学 2023-03-28 CN claimed
CN-109001345-B High performance liquid chromatography fluorescence detection method for determining concentration of perfluorooctanoic acid in landfill leachate 重庆大学 2022-06-17 CN claimed
CN-114213407-A 2-pyridyl thiazole hydrazone coumarin derivative chemical sensor, preparation method and application 江苏海洋大学 2022-03-22 CN claimed
CN-108774277-B Thiazole derivative containing glucosamine and coumarin molecules, and preparation method and application thereof 淮海工学院 2021-12-21 CN claimed
CN-108558851-B Coumarin-oxazole-ethylene type alpha-glucosidase inhibitor and preparation method and application thereof 贵州医科大学 2021-03-05 CN claimed
CN-108341809-B Steel rust inhibitor and preparation method and application thereof 内江师范学院 2020-12-22 CN claimed
CN-108558843-B Coumarin-triazole-isatin type compound and preparation method and application thereof 贵州医科大学 2020-12-15 CN claimed
CN-108598533-B Coumarin-based photocyclization crosslinking sulfonated polyimide proton exchange membrane and preparation method thereof 同济大学 2020-11-03 CN claimed
US-9127092-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2015-09-08 US claimed
US-20140187725-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2014-07-03 US claimed
EP-0620500-A2 Resist and pattern formation using the same HITACHI, LTD. (JP) 1994-10-19 EP claimed
US-20260034227-A1 AZLACTONE-BASED POLYMERS AS A SCAFFOLD FOR DIVERSE APPLICATIONS IN DRUG AND GENE DELIVERY UNIV MISSISSIPPI (US) 2026-02-05 US disclosed
CN-118834490-A Photo-crosslinkable perfluorinated ion membrane and preparation method thereof 上海交通大学 2024-10-25 CN disclosed
US-20240327655-A1 DYE-LABELED POLYMERS AND METHODS FOR PREPARING SAME DEBOGY MOLECULAR, INC. (US) 2024-10-03 US disclosed
EP-0620500-A2 Resist and pattern formation using the same HITACHI, LTD. (JP) 1994-10-19 EP disclosed
US-4001224-A 4-SUBSTITUTED-2, 3-DIHYDRO-1-BENZOXEPIN-3, 5-DIONES AND TAUTOMERS WARNER-LAMBERT COMPANY (US) 1977-01-04 US disclosed
US-3991082-A 4-Substituted-2,3-dihydro-1-benzoxepin-3,5-diones and tautomers WARNER-LAMBERT COMPANY (US) 1976-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034227-A1 AZLACTONE-BASED POLYMERS AS A SCAFFOLD FOR DIVERSE APPLICATIONS IN DRUG AND GENE DELIVERY SARS1, ATF4, PSD LMNA 332/4885MAOB 4473/4885CA12 2851/4885
US-20240327655-A1 DYE-LABELED POLYMERS AND METHODS FOR PREPARING SAME ALG1, CD99, GUSB LMNA 1610/4885MAOB 1060/4885CA12 514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.