Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CCR9 | P51686 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25007317 | 0.86 | CES1 (0.48) | NPC1LMNA | |
| SCHEMBL25007318 | 0.84 | CYP19A1 (0.55) | SMN1; SMN2CYP19A1TDP1MEN1KMT2A | |
| SCHEMBL30222651 | 0.79 | CES2 (0.47) | SMN1; SMN2MEN1KMT2AGRM5NPC1 | |
| SCHEMBL25007300 | 0.79 | CES2 (0.47) | SMN1; SMN2MEN1KMT2AGRM5NPC1 | |
| SCHEMBL9314754 | 0.78 | MAPT (0.47) | SMN1; SMN2TDP1MEN1KMT2AMAPT | |
| SCHEMBL9315537 | 0.75 | KIF11 (0.44) | SMN1; SMN2CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL20591894 | 0.75 | MEN1 (0.41) | SMN1; SMN2CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL9771667 | 0.74 | ACHE (0.42) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL3888184 | 0.74 | SCN5A (0.49) | SMN1; SMN2CYP19A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL9315815 | 0.73 | ACHE (0.41) | SMN1; SMN2MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4380920-A1 | INHIBITORS FOR CORONAVIRUSES | Cocrystal Pharma, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| CN-118103351-A | Coronavirus inhibitors | 共晶制药公司 | 2024-05-28 | — | — | CN | disclosed |
| WO-2023014758-A1 | INHIBITORS FOR CORONAVIRUSES | COCRYSTAL PHARMA, INC. (US) | 2023-02-09 | — | — | WO | disclosed |