SCHEMBL9315537

SCHEMBL9315537

O=C(O)C(F)(F)c1cccc(Cl)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.44
MPO P05164 1/20 0.42
MEN1 O00255 3/20 0.41
MAPT P10636 3/20 0.41
KMT2A Q03164 3/20 0.41
CYP1A2 P05177 2/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SLC22A12 Q96S37 1/20 0.41
PARP1 P09874 1/20 0.41
CYP19A1 P11511 1/20 0.41
LMNA P02545 2/20 0.41
HTT P42858 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
PPARG P37231 3/20 0.40
SCN5A Q14524 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17294833 0.90 KCNN4 (0.40) KIF11MPOMEN1MAPTKMT2A
SCHEMBL16346695 0.87 SCN5A (0.42) KIF11SLC22A12CYP19A1PPARGSCN5A
SCHEMBL13199336 0.86 PGK1 (0.48) MEN1MAPTKMT2ACYP1A2ALDH1A1
SCHEMBL20591894 0.85 MEN1 (0.41) KIF11MPOMEN1MAPTKMT2A
SCHEMBL3888184 0.83 SCN5A (0.49) KIF11MEN1MAPTKMT2ACYP1A2
SCHEMBL25007317 0.82 CES1 (0.48) KIF11PARP1LMNANPC1RAB9A
SCHEMBL31560780 0.81 PKM (0.44) KIF11MPOMEN1MAPTKMT2A
SCHEMBL28603099 0.81 PKM (0.44) KIF11MPOMEN1MAPTKMT2A
Bromomethane SCHEMBL4026722 0.80 KIF11 (0.41) KIF11MPOMEN1MAPTKMT2A
SCHEMBL30032454 0.80 PTPN1 (0.50) KIF11MPOMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10483466-B2 P-doping cross-linking of organic hole transporters SIEMENS AKTIENGESELLSCHAFT (DE) 2019-11-19 US claimed
EP-3114715-B1 P-DOPING CROSS-LINKING OF ORGANIC HOLE TRANSPORTERS SIEMENS AG (DE) 2019-10-30 EP claimed
US-20180198069-A1 P-Doping Cross-Linking Of Organic Hole Transporters SIEMENS AKTIENGESELLSCHAFT (DE) 2018-07-12 US claimed
EP-3114715-A1 P-DOPING CROSS-LINKING OF ORGANIC HOLE TRANSPORTERS Siemens Aktiengesellschaft (DE) 2017-01-11 EP claimed
US-20250185502-A1 ORGANIC OPTOELECTRONIC COMPONENT, ORGANIC FUNCTIONAL LAYER, AND METHOD FOR PRODUCING AN OPTOELECTRONIC COMPONENT OSRAM OLED GMBH (DE) 2025-06-05 US disclosed
US-12302747-B2 Optoelectronic component, organic functional layer, and method for producing an optoelectronic component OSRAM OLED GMBH (DE) 2025-05-13 US disclosed
EP-4193399-B1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2025-01-29 EP disclosed
EP-3210248-B2 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2024-04-10 EP disclosed
CN-111170991-B Antiproliferative compounds and methods of synthesis thereof 细胞基因公司 2023-10-31 CN disclosed
US-20230339934-A1 PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS RAQUALIA PHARMA INC. (JP) 2023-10-26 US disclosed
US-20230339934-A1 PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS RAQUALIA PHARMA INC. (JP) 2023-10-26 US disclosed
EP-3594211-B1 ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF CELGENE CORP (US) 2023-10-25 EP disclosed
US-20150162534-A1 METAL COMPLEXES AS P-TYPE DOPANTS FOR ORGANIC ELECTRONIC MATRIX MATERIALS OSRAM OLED GMBH (DE) 2015-06-11 US disclosed
CN-104685647-A Main group metal complexes as p-dopants for organic electronic matrix materials SIEMENS AG 2015-06-03 CN disclosed
US-20150123047-A1 MAIN GROUP METAL COMPLEXES AS P-DOPANTS FOR ORGANIC ELECTRONIC MATRIX MATERIALS OSRAM OLED GMBH (DE) 2015-05-07 US disclosed
CN-104541383-A Metal complexes as p-type dopants for organic electronic matrix materials SIEMENS AG 2015-04-22 CN disclosed
CN-102399227-A Synthesis process of anti-tumor novel medicine 3- { (3-chlorphenyl) difluoromethyl-1-isopropyl-1H-pyrazolo (3,4-D) pyrimidine-4-amine compound SHENGSHI TAIKE BIOMEDICAL TECHNOLOGY SUZHOU CO LTD 2012-04-04 CN disclosed
US-5300527-A Administering anticholinergic agents for treating the memory dysfunction HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1994-04-05 US disclosed
US-5177111-A Analgesic HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1993-01-05 US disclosed
US-5006563-A Alzheimer's disease HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1991-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339934-A1 PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS TRPV4, TRPV1, TRPV2 KIF11 4276/4885MPO 4078/4885MEN1 3786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.