SCHEMBL30223441

SCHEMBL30223441

Clc1ccccc1-c1cccc(Br)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 1/20 0.43
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
RAB9A P51151 1/20 0.43
MAOB P27338 2/20 0.42
SCN9A Q15858 1/20 0.42
BACE1 P56817 1/20 0.41
TRPA1 O75762 1/20 0.41
MAOA P21397 1/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPK10 P53779 2/20 0.40
MAPK14 Q16539 2/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26570560 1.00 CYP2A6 (0.58) CYP2A6SMN1; SMN2NPC1TP53TSHR
SCHEMBL9479255 0.84 CYP2A6 (0.71) CYP2A6SMN1; SMN2NPC1TP53TSHR
SCHEMBL29628996 0.84 CYP2A6 (0.71) CYP2A6SMN1; SMN2NPC1TP53TSHR
SCHEMBL29398181 0.84 RAB9A (0.50) SMN1; SMN2NPC1TP53TSHRRAB9A
SCHEMBL5805651 0.84 RAB9A (0.50) SMN1; SMN2NPC1TP53TSHRRAB9A
SCHEMBL25740852 0.84 CYP2A6 (0.50) CYP2A6SMN1; SMN2NPC1TP53TSHR
SCHEMBL29054494 0.82 KMO (0.38) CYP2A6SMN1; SMN2NPC1TP53TSHR
SCHEMBL16173656 0.82 RAB9A (0.48) SMN1; SMN2NPC1TP53TSHRRAB9A
SCHEMBL1743996 0.81 CYP2A6 (0.50) CYP2A6SMN1; SMN2NPC1TP53TSHR
SCHEMBL2278862 0.80 ALDH1A1 (0.52) SMN1; SMN2NPC1TP53TSHRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4618755-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2025-09-24 EP disclosed
WO-2024107746-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES (US) 2024-05-23 WO disclosed
WO-2023002447-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 WO disclosed