Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 6/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1180659 | 0.80 | KDM4E (0.62) | CYP3A4KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL8802227 | 0.77 | KDM4E (0.59) | CYP3A4KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL4757017 | 0.77 | LMNA (0.61) | CYP3A4KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL30224972 | 0.77 | CYP3A4 (0.54) | CYP3A4KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL2746872 | 0.76 | MEN1 (0.90) | CYP3A4KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL752884 | 0.74 | KDM4E (0.65) | CYP3A4KDM4EMEN1KMT2AMAPK1 | |
| Flavonol SCHEMBL20246 | 0.74 | KDM4E (1.00) | CYP3A4KDM4EMEN1KMT2AMAPK1 | |
| Flavonol SCHEMBL1679068 | 0.74 | KDM4E (1.00) | CYP3A4KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL2355971 | 0.74 | CA1 (0.65) | CYP3A4KDM4EMEN1KMT2AMAPK1 | |
| SCHEMBL4696277 | 0.74 | MAOA (0.90) | CYP3A4KDM4EMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107641109-B | A kind of flavonoids and its preparation method and application | 厦门大学 | 2019-05-24 | — | — | CN | disclosed |