Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228504 | 0.84 | ALDH1A1 (0.52) | KCNA3ALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL30227920 | 0.82 | KCNA3 (0.53) | KCNA3ALDH1A1TDP1NPC1MAOA | |
| SCHEMBL30228405 | 0.80 | CA9 (0.56) | KCNA3ALDH1A1MAPTMAOAMAOB | |
| SCHEMBL30231539 | 0.76 | IGLV6-57 (0.44) | KCNA3ALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL30228286 | 0.75 | KCNA3 (0.47) | KCNA3ALDH1A1MAPTMAOAHPGD | |
| SCHEMBL30228422 | 0.74 | KCNA3 (0.46) | KCNA3ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL31711138 | 0.71 | MAPT (0.42) | KCNA3ALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL30228381 | 0.69 | KCNA3 (0.56) | KCNA3ALDH1A1SMN1; SMN2TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL30228355 | 0.68 | KCNA3 (0.55) | KCNA3ALDH1A1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL30228412 | 0.68 | KCNA3 (0.62) | KCNA3ALDH1A1SMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |